Antidiarrhoeal Activity of  Decoction of Scoparia dulcis in Rats

dc.contributor.author	Ratnasooriya, W.D.
dc.contributor.author	Galhena, G.
dc.contributor.author	Liyanage, S.S.P.
dc.contributor.author	Jayakody, J.R.A.C.
dc.contributor.author	Hettiarachchi, A.D.I.
dc.contributor.author	Ediriweera, E.R.S.S.
dc.date.accessioned	2013-05-02T05:32:40Z
dc.date.available	2013-05-02T05:32:40Z
dc.date.issued	2005
dc.identifier.citation	Ratnasooriya, W.D., Galhena, G., Liyanage, S.S.P., Jayakody, J.R.A.C., Hettiarachchi, A.D.I., & Ediriweera, E.R.S.S. (2005). Antidiarrhoeal Activity of Decoction of Scoparia dulcis in Rats. Vidyodaya Journal of Science, 12, 57-63.	en-US
dc.identifier.uri	http://dr.lib.sjp.ac.lk/handle/123456789/1031
dc.description.abstract	The aim of this study was to investigate the antidiarrhoeal potential of a decoction (D) made from Scoparia dulcis Linn (Family: Scrophulariaceae), as indicated by traditional practitioners in Sri Lanka, using the caster oil-induced diarrhoeal rat model. Different doses ofD (500,1500,3000 rng/kg) were orally administrated and antidiarrhoeal activity monitored over a 6 h period. The D induced a significant (P<0,05) and dose- dependent antidiarrhoeal effect from Ih post treatment. This antidiarrhoeal action was mediated via an inhibition in intestinal transit due to impairment of intestinal peristalsis, rather than to an increment in intestinal fluid absorption and/or reduction in secretion. The decoction may have a potential in symptomatic relief of non-specific acute diarrhoeas.	en_US
dc.language.iso	en	en_US
dc.subject	Scoparla dulcis	en_US
dc.subject	Antidiarrhoeal activity	en_US
dc.subject	Peristalsis	en_US
dc.subject	Intestinal transit	en_US
dc.subject	Traditional medicine	en_US
dc.title	Antidiarrhoeal Activity of Decoction of Scoparia dulcis in Rats	en_US
dc.type	Article	en_US
dc.date.published	2005