dc.contributor.author |
Branavan, U. |
|
dc.contributor.author |
Wijesundera, S. |
|
dc.contributor.author |
Chandrasekharan, V. |
|
dc.date.accessioned |
2022-03-02T10:08:20Z |
|
dc.date.available |
2022-03-02T10:08:20Z |
|
dc.date.issued |
2021-05-31 |
|
dc.identifier.citation |
Branavan, U. , et al.(2021)."Potential Genetic Polymorphisms Predicting Polycystic Ovary Syndrome (PCOS) in Sri Lankan Women: Comparison with Different Ethnicity" Advances In Technology,1(1), 65-88 |
en_US |
dc.identifier.uri |
http://dr.lib.sjp.ac.lk/handle/123456789/10386 |
|
dc.description.abstract |
Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder of young women with long-term metabolic risk and prevalence among pre-marital Sri Lankan women is 6.3%. Inheritance of PCOS is likely to be oilgogenic; the genetic basis remaining largely unknown in view of the complex pathophysiology. The genetics of expression of PCOS requires an in-depth study, particularly among Sri Lankan women who have a greater metabolic risk from an early age. The emergence of an unanimously accepted genetic marker for susceptible PCOS was affected based on inconsistent findings. In this review, we summarize the common genetic polymorphisms of PCOS from different countries and outline some genetic polymorphisms that are potentially associated with the risk of PCOS in Sri Lankan women. This information could uncover candidate genes associating with PCOS, which will be valuable for the development of novel diagnostic and treatment method. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Faculty of Technology, USJ |
en_US |
dc.subject |
Hypothalamic pituitary gonadal axis, polycystic ovary syndrome, single nucleotide polymorphism |
en_US |
dc.title |
Potential Genetic Polymorphisms Predicting Polycystic Ovary Syndrome (PCOS) in Sri Lankan Women: Comparison with Different Ethnicity |
en_US |
dc.type |
Article |
en_US |
dc.identifier.doi |
https://doi.org/10.31357/ait.v1i1.4889 |
en_US |