Abstract:
This case report deals with a patient managed
in a tertiary-care cancer hospital who
suffered pruritus associated with malignant
cholestasis. His symptoms were resistant to
conventional treatment with ursodeoxycholic
acid, chlorpheniramine and cholestyramine.
Hence, the multifactorial origin of malignancyassociated pruritus was considered. Correctable
factors were corrected and generally the
treatment was aimed at possible aetiologies.
There were barriers related to insufficient
resources available for symptom palliation in this
particular setting, which could potentially reduce
optimum symptom control. However, various
pharmacotherapies and non-pharmacological
measures which could potentially have helped
relieve pruritus are described and future scope
for research in this area discussed
