Attached
Centella asiatica (Umbelliferae) and Aegle marmelos
(Rutaceae) are widely used as a ve~etable and a fruit respectively. These two plants are used in Ayurvedic and indigenous
medicinal systems in Sri Lanka.
Earlier researchers have reported the effect of aqueous
extracts of these two plants on the classical and alternative
pathways of activation of human complement in vitro. Activity
directed fractionation of the aqueous extracts indicated that
most of the activity was confined to the polysaccharide fraction.
This thesis reports the preliminary chemical analysis of the
polysaccharide fraction of Centella asiatica and Ae~le marmelos.
These polysaccharides were hydrolysed and methanolysed. T.L.C
and H.P.L.C analysis were done for analysing their monomer
composition. The immunomodulating activity and Biological activity
of these fractions using the .~emia bio assay were studied.