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Antireproductive Effects in Male Rats Exposed to Methamidophos

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dc.contributor.author Peiris, L.D.C.
dc.contributor.author Jayatunga, Y.N.A.
dc.contributor.author Ratnasooriya, W.D.
dc.date.accessioned 2016-12-01T06:23:55Z
dc.date.available 2016-12-01T06:23:55Z
dc.date.issued 1995
dc.identifier.citation Peiris, L.D.C., Jayatunga, Y.N.A., & Ratnasooriya, W.D. (1995). Ant Reproductive Effects in Male Rats Exposed to Methamidophos. Ceylon Journal of Science (Biological Sciences), 24(2), 53-59. en_US, si_LK
dc.identifier.issn 2513-2814
dc.identifier.uri http://dr.lib.sjp.ac.lk/handle/123456789/3497
dc.description.abstract This study examined the reproductive effects of methamidophos, an organophosphorus pesticide on male rats following sub-chronic oral administration (in 3 alternate days). The doses tested were 1.8750 and 0.9375 mg kg"1 day"1 and the reproductive effects were investigated upto 28 - 35 days post-treatment. The results show that both doses of methamidophos inhibited libido in a reversible fashion lasting upto 28 – 35 days. This effect on libido was accompanied by marked depressions in food and water intake, body weight and by cholinergic intoxication. Furthermore, the treatment was reprotoxic: decreased testicular interstitial fluid volume, seminiferous tubular diameter and reduction in motility and numbers of cauda epididymal sperm. Based on these data it is concluded that methamidophos could be detrimental to the sexuality and fertility of men who are constantly exposed to it. en_US, si_LK
dc.language.iso en en_US, si_LK
dc.publisher University of Peradeniya, Peradeniya. en_US, si_LK
dc.title Antireproductive Effects in Male Rats Exposed to Methamidophos en_US, si_LK
dc.type Article en_US, si_LK


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