Survival after severe amitriptyline poisoning with prolonged ventricular tachycardia and cardiac arrest

dc.contributor.author	Abeyaratne, D.D.K.
dc.contributor.author	Liyanapathirana, C.
dc.contributor.author	Gamage, A.
dc.contributor.author	Karunarathne, P.
dc.contributor.author	Botheju, M.
dc.contributor.author	Indrakumar, J.
dc.date.accessioned	2017-10-03T11:12:30Z
dc.date.available	2017-10-03T11:12:30Z
dc.date.issued	2016-03-15
dc.identifier.citation	Abeyaratne, D.D.K., Liyanapathirana, C., Gamage, A., Karunarathne, P., Botheju, M., Indrakumar, J. (2016). "Survival after severe amitriptylinepoisoning with prolonged ventricular tachycardia and cardiac arrest", BMC Res Notes, Vol.9, 5 P.	en_US, si_LK
dc.identifier.uri	http://dr.lib.sjp.ac.lk/handle/123456789/5595
dc.description.abstract	Attached	en_US, si_LK
dc.description.abstract	Background: Tricyclic antidepressants (TCA) are becoming one of the most frequently used substances in self poisoning. Significant morbidity and mortality associated with TCA overdose are often related to and refractory hypotension. We report the first case of survival after severe amitriptyline poisoning, leading to prolonged cardiac arrest and ventricular tachycardia (VT), resuscitated with 3 h of uninterrupted cardiac massage and Direct current (DC) shocks. Case presentation: A 25 year old girl presented with severe amitriptyline poisoning causing pulseless VT and prolonged cardiac arrest. After 3 h of uninterrupted external cardiac massage, together with nine DC shocks and intra venous bicarbonate injections the rhythm reverted to a nodal tachycardia, initial 2D echocardiogram showed left ventricular dysfunction, which recovered to normal after 2 weeks and the patient had a complete recovery subsequently. Conclusion: Our case highlights the importance of continued resuscitation in patients presenting with TCA poisoning and resistant arrhythmia, especially in young and otherwise healthy patients. Keywords: Tricyclic antidepressants, Cardiac arrhythmia, Prolonged cardiac arrest
dc.language.iso	en_US	en_US, si_LK
dc.publisher	BMC Res Notes	en_US, si_LK
dc.subject	Tricyclic antidepressants	en_US, si_LK
dc.subject	Cardiac arrhythmia	en_US, si_LK
dc.subject	Prolonged cardiac arrest	en_US, si_LK
dc.title	Survival after severe amitriptyline poisoning with prolonged ventricular tachycardia and cardiac arrest	en_US, si_LK
dc.type	Article	en_US, si_LK