Investigation of Ethyl Acetate Soluble Pro an thocyanidins in the Inflorescence of Cocos nucifera L.

dc.contributor.author	Padumadasa, C.
dc.contributor.author	Dharmadana, D.
dc.contributor.author	Abeysekera, A.M.
dc.contributor.author	Thammitiyagodage, M.G.
dc.date.accessioned	2017-10-23T05:10:54Z
dc.date.available	2017-10-23T05:10:54Z
dc.date.issued	2015
dc.identifier.citation	Padumadasa, C., Dharmadana, D., Abeysekera, A.M., Thammitiyagodage, M.G. (2015). "Investigation of Ethyl Acetate Soluble Pro an thocyanidins in the Inflorescence of Cocos nucifera L.", Journal of Pharmacognosy and Phytochemistry, Vol.4 (2), pp. 107-111	en_US, si_LK
dc.identifier.issn	2278-4136
dc.identifier.issn	2349-8234
dc.identifier.uri	http://dr.lib.sjp.ac.lk/handle/123456789/6017
dc.description.abstract	Attached	en_US, si_LK
dc.description.abstract	The immature inflorescence of Cocos nucifera L. variety aurantiaca is used in Ayurveda for the treatment of menorrhagia in Sri Lanka. Preliminary phytochemical screening revealed that immature inflorescence predominantly contains proanthocyanidins. TTie ethyl acetate soluble proanthocyanidin (EASPA' f action obtained from an acetone/water (7:3) extract of the immature inflorescence was effectively purified and separated from other phenolic compounds by chromatography on sephadex LH-20. EASPA has been fully characterized by chromatographic, spectroscopic and spectrometric methods. Acid catalyzed cleavage followed by TLC indicated that EASPA is composed of (epi)catechin and (epi)afeelechin monomeric units while thiolysis followed by ‘H and 13C NMR spectroscopy revealed the monomers to be the epi-isomers. I3C NMR studies of EASPA showed signals characteristic for epicatechin units indicating that EASPA is composed mainly of epicatechin units. Confirming these epicatechin oligomers with degrees of polymerization ranging from 2-5 and mixed oligomers, epicatechin-epiafzelechin dimer and epicatechin-epicatechin-epiafzelechin trimer were observed by ESI-MS.
dc.language.iso	en_US	en_US, si_LK
dc.publisher	Journal of Pharmacognosy and Phytochemistry	en_US, si_LK
dc.subject	Cocos nucifera inflorescence	en_US, si_LK
dc.subject	proanthocyanidin	en_US, si_LK
dc.subject	epicatechin	en_US, si_LK
dc.subject	epiafzelechin	en_US, si_LK
dc.subject	thiolysis	en_US, si_LK
dc.title	Investigation of Ethyl Acetate Soluble Pro an thocyanidins in the Inflorescence of Cocos nucifera L.	en_US, si_LK
dc.type	Article	en_US, si_LK