dc.contributor.author |
Piyathilaka, P.C. |
|
dc.contributor.author |
Tennekoon, K.H. |
|
dc.contributor.author |
De Silva, N.K. |
|
dc.contributor.author |
Manage, P.M. |
|
dc.date.accessioned |
2017-10-26T05:44:54Z |
|
dc.date.available |
2017-10-26T05:44:54Z |
|
dc.date.issued |
2016 |
|
dc.identifier.citation |
Piyathilaka, P.C., Tennekoon, K.H., De Silva, N.K., Manage, P.M. (2016). "Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.", ISOI Journal Of Microbiology, Biotechnology And Food Science, Vol.2 (1), pp. 45-49 |
en_US, si_LK |
dc.identifier.issn |
2395-6887 |
|
dc.identifier.uri |
http://dr.lib.sjp.ac.lk/handle/123456789/6162 |
|
dc.description.abstract |
Attached |
en_US, si_LK |
dc.description.abstract |
The aim of present study was to evaluate the cytotoxic effects of some
selected cyanotoxins namely, MC-LR, MC-RR, MC-LF, MC-LW and Nodularin
on normal human kidney cells (HEK-293) and human kidney adenocarcinoma
cells (ACHN). Cells were exposed to different concentrations of (1.0-200 pM )
cyanotoxin variants for 24 h and the cytotoxic effects were evaluated by
Sulphorhodamine B (SRB) assay. Overall findings of the study demonstrate
that cyanotoxins could cause cytotoxic effects on kidney cells. MC-LR was
the most toxic while MC-LW was least toxic cyanotoxin on both cell types
tested. MC-RR, MC-LF and Nodularin had moderate cytotoxicity on human
renal cells. |
|
dc.language.iso |
en_US |
en_US, si_LK |
dc.publisher |
ISOI Journal Of Microbiology, Biotechnology And Food Science |
en_US, si_LK |
dc.subject |
Cytotoxicity |
en_US, si_LK |
dc.subject |
ACHN cells |
en_US, si_LK |
dc.subject |
HEK-293 cells |
en_US, si_LK |
dc.subject |
SRB |
en_US, si_LK |
dc.subject |
Cyanotoxins |
en_US, si_LK |
dc.title |
Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells. |
en_US, si_LK |
dc.type |
Article |
en_US, si_LK |