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Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.

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dc.contributor.author Piyathilaka, P.C.
dc.contributor.author Tennekoon, K.H.
dc.contributor.author De Silva, N.K.
dc.contributor.author Manage, P.M.
dc.date.accessioned 2017-10-26T05:44:54Z
dc.date.available 2017-10-26T05:44:54Z
dc.date.issued 2016
dc.identifier.citation Piyathilaka, P.C., Tennekoon, K.H., De Silva, N.K., Manage, P.M. (2016). "Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.", ISOI Journal Of Microbiology, Biotechnology And Food Science, Vol.2 (1), pp. 45-49 en_US, si_LK
dc.identifier.issn 2395-6887
dc.identifier.uri http://dr.lib.sjp.ac.lk/handle/123456789/6162
dc.description.abstract Attached en_US, si_LK
dc.description.abstract The aim of present study was to evaluate the cytotoxic effects of some selected cyanotoxins namely, MC-LR, MC-RR, MC-LF, MC-LW and Nodularin on normal human kidney cells (HEK-293) and human kidney adenocarcinoma cells (ACHN). Cells were exposed to different concentrations of (1.0-200 pM ) cyanotoxin variants for 24 h and the cytotoxic effects were evaluated by Sulphorhodamine B (SRB) assay. Overall findings of the study demonstrate that cyanotoxins could cause cytotoxic effects on kidney cells. MC-LR was the most toxic while MC-LW was least toxic cyanotoxin on both cell types tested. MC-RR, MC-LF and Nodularin had moderate cytotoxicity on human renal cells.
dc.language.iso en_US en_US, si_LK
dc.publisher ISOI Journal Of Microbiology, Biotechnology And Food Science en_US, si_LK
dc.subject Cytotoxicity en_US, si_LK
dc.subject ACHN cells en_US, si_LK
dc.subject HEK-293 cells en_US, si_LK
dc.subject SRB en_US, si_LK
dc.subject Cyanotoxins en_US, si_LK
dc.title Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells. en_US, si_LK
dc.type Article en_US, si_LK


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