Worsening cholestasis and possible cefuroxime-induced liver injury following "successful" therapeutic endoscopic retrograde cholangiopancreatography for a distal common bile duct stone: a case report

dc.contributor.author	Niriella, M.A.
dc.contributor.author	Kumarasena, R.S.
dc.contributor.author	Dassanayake, A.S.
dc.contributor.author	Pathirana, A.
dc.contributor.author	Hewavisenthi, J.D.
dc.contributor.author	De Silva, H.J.
dc.date.accessioned	2017-11-02T03:53:24Z
dc.date.available	2017-11-02T03:53:24Z
dc.date.issued	2016-12-21
dc.identifier.citation	Niriella, M.A., Kumarasena, R.S., Dassanayake, A.S., Pathirana, A., Hewavisenthi, J.D., De Silva, H.J. (2016). "Worsening cholestasis and possible cefuroxime-induced liver injury following "successful" therapeutic endoscopic retrograde cholangiopancreatography for a distal common bile duct stone: a case report", Journal of Medical Case Reports, Vol.10, pp. 01-04	en_US, si_LK
dc.identifier.uri	http://dr.lib.sjp.ac.lk/handle/123456789/6406
dc.description.abstract	Attached	en_US, si_LK
dc.description.abstract	Background: Cefuroxime very rarely causes drug-induced liver injury. We present a case of a patient with paradoxical worsening of jaundice caused by cefuroxime-induced cholestasis following therapeutic endoscopic retrograde cholangiopancreatography for a distal common bile duct stone. Case presentation: A 51-year-old, previously healthy Sri Lankan man presented to our hospital with obstructive jaundice caused by a distal common bile duct stone. Endoscopic retrograde cholangiopancreatography with stone extraction, common bile duct clearance, and stenting failed to improve the cholestasis, with paradoxical worsening of his jaundice. A liver biopsy revealed features of drug-induced intrahepatic cholestasis. Although his case was complicated by an episode of cholangitis, the patient made a complete recovery in 4 months with supportive treatment and withdrawal of the offending drug. Conclusions: This case highlights a very rare drug-induced liver injury caused by cefuroxime as well as our approach to treating a patient with paradoxical worsening of jaundice after therapeutic endoscopic retrograde cholangiopancreatography
dc.language.iso	en_US	en_US, si_LK
dc.publisher	Journal of Medical Case Reports	en_US, si_LK
dc.subject	Cefuroxime	en_US, si_LK
dc.subject	Drug-induced liver injury	en_US, si_LK
dc.subject	Cholestasis	en_US, si_LK
dc.subject	ERCP	en_US, si_LK
dc.title	Worsening cholestasis and possible cefuroxime-induced liver injury following "successful" therapeutic endoscopic retrograde cholangiopancreatography for a distal common bile duct stone: a case report	en_US, si_LK
dc.type	Article	en_US, si_LK