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Introduction : Inflammatory pseudotumour is a rare, chronic inflammatory disorder and is not
considered a true neoplasm. It is frequently encountered in the first two decades o f life and is
related to an infective process or a foreign body reaction. Clinical behavior is unpredictable,
ranging from benign to a locally aggressive lesion.
Case history : A 20 year old female presented with a vague, right side loin pain for 2 months
duration. She was diagnosed as having a retroperitoneal mass attached to the right adrenal gland
by imaging studies.
Pathological findings : Resected specimen was a well-circumscribed, yellow-brown soft tissue
mass weighing 19.1g and measuring 37 x 25x 15mm. Microscopic examination showed a spindle
cell lesion mixed with plasma cells, lymphocytes, histiocytes and foreign body giant cells. Focal
myxoid change, reactive vascular proliferation and a large area o f necrosis was seen. The mitotic
count was <1/10 high power fields.
Discussion : Histological differential diagnoses included an inflammatory pseudotumour, a lowH'mde-sarcoma, a solitary fibrous tumour or a chronic granulomatous condition.
Immunohistochemistry showed negativity for CD 34 and desmin and focal positivity for SMA.
I tie Ki 67 index was < 2%.
