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Infection with H. pylori is considered a major cause of chronic
gastritis,, peptic ulcer disease and gastric cancer. More than half of the world population is infected with H. pylori and a 709c
prevalence has been reported from Sri Lanka. Due to the difficulty
in culture and Antibiotic Susceptibility Testing in the laboratory, it
is treated empirically using clarythromycin as part of the triple
therapy. The resistance to these antibiotics in Sri Lanka are not
known. Thus it is of paramount importance to determine the
clarithromycin resistance of H. priori in Sri Lanka. The aim of this
study was to determine the current proportion of H. pylori and to
investigate the clarithromycin resistant A2142G and A2143G
mutations present in the 23S rRNA gene of H. pylon strains. Further
the risk factors for infecticffwffliT/. pylori were investigated