Abstract:
Hypotensive properties of the crude extract of Sri Lankan marine red algae
Gracilaria sp. of the family Gracilaracea were investigated on anaesthetized rats
using two doses (250 or 500mg/kg) given intraperitoneally. The results show
that the crude extract possesses antihypertensive properties. The extract induced
an immediate fall in systolic blood pressure (within 5 min) which was shortlived
with the lower dose and sustained with the higher dose. The precise mode
of the antihypertensive action is uncertain but is likely to be mediated via decreased
sympathetic activity.
