Toxic Effetcts on Biochemical and Hematological Parametera in Rats Exposed to Judo 40.

dc.contributor.author	Kudavidanage, I.
dc.contributor.author	Peiris, L.D.C.
dc.date.accessioned	2019-01-09T06:25:41Z
dc.date.available	2019-01-09T06:25:41Z
dc.date.issued	2017
dc.identifier.citation	Kudavidanage, I., Peiris, L.D.C., (2017)." Toxic Effet=cts on Biochemical and Hematological Parametera in Rats Exposed to Judo 40",International Journal of Advanced Research. Vol.5(12), pp.156-160	en_US
dc.identifier.issn	2320-5407
dc.identifier.uri	http://dr.lib.sjp.ac.lk/handle/123456789/8047
dc.description.abstract	attached	en_US
dc.description.abstract	The present study investigated the hematological, and biochemical, changes due to Judo 40 toxicity in male Wistar albino rats. Two sets of male rats (n=9/group) were orally treated with 20 mg/kg and 50 mg/kg of Judo 40 or the vehicle (corn oil) in four fractions for two consecutive days. The first of animals were autopsied on day 1 to assess the liver toxicity while the second set of animals were autopsied on posttreatment day 3 to assess hematological parameters. Both doses of Judo 40 intoxication induced a significant increase in PCV, and WBCs count. Moreover, there was a significant increase in serum biochemical parameters related to hepatic injury: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP). In general, it was concluded that, Judo 40 could induce hepatotoxicity and alter PCV and WBC counts indicating exposure to Judo 40 could pose risk to human health.
dc.language.iso	en	en_US
dc.subject	Judo 40	en_US
dc.subject	hematological parameters	en_US
dc.subject	ALT	en_US
dc.subject	AST	en_US
dc.subject	ALP	en_US
dc.title	Toxic Effetcts on Biochemical and Hematological Parametera in Rats Exposed to Judo 40.	en_US
dc.type	Article	en_US