dc.contributor.author |
Ratnayake, W.M.K.M. |
|
dc.contributor.author |
Suresh, T.S. |
|
dc.contributor.author |
Abeysekera, A.M. |
|
dc.contributor.author |
Salim, N. |
|
dc.contributor.author |
Chandrika, U.G. |
|
dc.date.accessioned |
2019-06-06T05:00:50Z |
|
dc.date.available |
2019-06-06T05:00:50Z |
|
dc.date.issued |
2018 |
|
dc.identifier.citation |
Ratnayake, W.M.K.M. et al., Acute anti-intlammatory activity of evolitrine isolated from Acronychia pedunculata leaves in Wistar rats, Sixth annual scientific sessions, Sri Lanka Association for Laboratory Animal Acience, 2018 |
en_US |
dc.identifier.uri |
http://dr.lib.sjp.ac.lk/handle/123456789/8382 |
|
dc.description.abstract |
Attached |
en_US |
dc.description.abstract |
Introduction
As a result of the adverse effects caused by existing allopathic anti – inflammatory agents, investigations on the efficacy of plant based drugs have been seen as a fruitful research strategy in the search for new alternatives. Acronychia pedunculata (“Ankenda” in Sinhala, Family: Rutaceae) is a medicinal plant which has been used for centuries in traditional/ folk medicine in Sri Lanka. Our previous studies have shown that 70% ethanol extract of leaves of this plant has significant anti-inflammatory activity on the carrageenan induced rat bind paw oedema test model.
Objective
In the present study, an attempt has been made to evaluate the anti-inflammatory activity of evolitrine which was isolated as a major alkaloid from A. pedunculata leaves, by using the same in-vivo model. |
|
dc.description.abstract |
Conclusion
As evolitrine alone has shown an enhancement of anti-inflammatory activity when compared to the initial crude extract, it was identified as a major anti-inflammatory compound present in A. pedunculata leaves |
|
dc.language.iso |
en |
en_US |
dc.title |
Acute anti-intlammatory activity of evolitrine isolated from Acronychia pedunculata leaves in Wistar rats |
en_US |
dc.type |
Article |
en_US |