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Maternal Vitamin D Status and Its Effect on Vitamin D Levels in Early Infancy in a Tertiary Care Centre in Sri Lanka

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dc.contributor.author Kaneshapillai, A
dc.contributor.author Hettiaratchi, U
dc.contributor.author Gunasekera, D
dc.contributor.author Prathapan, S
dc.contributor.author Liyanage, G
dc.date.accessioned 2022-02-07T04:54:48Z
dc.date.available 2022-02-07T04:54:48Z
dc.date.issued 2019
dc.identifier.citation Kaneshapillai, A, et al.(2019)."Maternal Vitamin D Status and Its Effect on Vitamin D Levels in Early Infancy in a Tertiary Care Centre in Sri Lanka", Hindawi International Journal of Endocrinology Volume 2019, Article ID 9017951, 6 pgs en_US
dc.identifier.uri http://dr.lib.sjp.ac.lk/handle/123456789/9967
dc.description.abstract Epidemiologic studies from South Asian countries have reported vitamin D defciency among all age groups. However, there is very little information on vitamin D levels, especially in the vulnerable populations (pregnant/breast feeding mother and infants) in Sri Lanka. More data on vitamin D status of such populations will be important for policy decisions to be made at a national level. Similarly, it will be valuable for healthcare programs in other countries (e.g., United States, Australia, Europe, and Canada) as Sri Lankans are a fast-growing migrant population to those countries. Te purpose of this study was to investigate maternal vitamin D status and its efects on infants in a state sector tertiary care centre in Sri Lanka. Tis prospective cohort study was conducted on 140 healthy pregnant mothers in the third trimester (mean gestational age 39±1 weeks). Blood was collected for 25(OH)D and parathyroid hormone (PTH). Sun exposure and feeding patterns of the infants were recorded based on maternal reporting. Mean age of the infants at follow-up visit was 36±7 days. Vitamin D (25 (OH)D) defciency (<25 nmol/L) was observed in 12% pregnant mothers, 5% lactating mothers, and 63% infants. Insufciency (<50 nmol/L) was found in an additional 51% and 43% in pregnant and lactating mothers and 25% of infants. Mean 25(OH)D was higher in pregnant (46.4±17.5 nmol/L) and lactating (51.9±17.0 nmol/L) mothers than infants (28.1±13.7 nmol/L). Maternal vitamin D level during pregnancy was a signifcant risk factor (OR: 6.00, 95%CI: 1.522-23.655) for infant defciency and insufciency. Sun exposure of infants showed a signifcant positive correlation with vitamin D level (OR: 3.23, 95%CI: 1.19-8.68). In conclusion, the presence of Vitamin D defciency/insufciency is higher in infants compared to pregnant/lactating mothers. Low maternal 25(OH)D during pregnancy was a risk factor for defciency in infants. Although majority of lactating mothers had sufcient vitamin D, most of their exclusively breastfed ofspring were defcient en_US
dc.language.iso en en_US
dc.publisher Hindawi International Journal of Endocrinology en_US
dc.title Maternal Vitamin D Status and Its Effect on Vitamin D Levels in Early Infancy in a Tertiary Care Centre in Sri Lanka en_US
dc.type Article en_US


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