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Synthesis, Characterization and Antimicrobial Activity of Garcinol Capped Silver Nanoparticles

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dc.contributor.author Fernando, H.N
dc.contributor.author Kumarasinghe, K.G.U.R
dc.contributor.author Gunasekara, T.D.C.P
dc.date.accessioned 2022-02-07T09:50:21Z
dc.date.available 2022-02-07T09:50:21Z
dc.date.issued 2019
dc.identifier.citation Fernando, H.N, et al.(2019)."Synthesis, Characterization and Antimicrobial Activity of Garcinol Capped Silver Nanoparticles", J. Microbiol. Biotechnol. (2019), 29(11), 1841–1851 en_US
dc.identifier.uri http://dr.lib.sjp.ac.lk/handle/123456789/10003
dc.description.abstract Garcinol, a well-known medicinal phytochemical, was extracted and isolated from the dried fruit rinds of Garcinia quaesita Pierre. In this study, garcinol has successfully used to reduce silver ions to silver in order to synthesize garcinol-capped silver nanoparticles (G-AgNPs). The formation and the structure of G-AgNPs were confirmed by UV-visible spectroscopy, transmission electron microscopy and Fourier transform infrared spectroscopy. The antimicrobial activity of garcinol and G-AgNPs were investigated by well diffusion assays, broth micro-dilution assays and time-kill kinetics studies against five microbial species, including Staphylococcus aureus (ATCC 25923), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922), Candida albicans (ATCC 10231) and clinically isolated methicillin-resistant Staphylococcus aureus (MRSA). The formation of G-AgNPs is a promising novel approach to enhancing the biological activeness of silver nanoparticles, and to increase the water solubility of garcinol which creates a broad range of therapeutic applications. en_US
dc.language.iso en en_US
dc.publisher J. Microbiol. Biotechnol. en_US
dc.subject Garcinol, silver nanoparticles, garcinol-capped silver nanoparticles, antimicrobial activity, time-kill kinetics studies en_US
dc.title Synthesis, Characterization and Antimicrobial Activity of Garcinol Capped Silver Nanoparticles en_US
dc.type Article en_US


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