dc.contributor.author |
Piyathilaka, P.C. |
|
dc.contributor.author |
Tennekoon, K.H. |
|
dc.contributor.author |
De Silva, N.K. |
|
dc.contributor.author |
Manage, P.M. |
|
dc.date.accessioned |
2016-09-26T08:15:13Z |
|
dc.date.available |
2016-09-26T08:15:13Z |
|
dc.date.issued |
2016-09-26T08:15:13Z |
|
dc.identifier.citation |
Piyathilaka, P.C., Tennekoon, K.H., De Silva, N.K., & Manage, P.M. (2016). Comparative Cytotoxicity of Selected Cyanotoxins on Human Embryonic Kidney (HEK-293) and Human Kidney Adenocarcinoma (ACHN) Cells. ISOI Journal of Microbiology, Biotechnology And Food Science, 2(1), 45-49. |
|
dc.identifier.issn |
2395-6887 |
|
dc.identifier.uri |
http://dr.lib.sjp.ac.lk/handle/123456789/2947 |
|
dc.description.abstract |
The aim of present study was to evaluate the cytotoxic effects of some selected cyanotoxins namely, MC-LR, MC-RR, MC-LF, MC-LW and Nodularin on normal human kidney cells (HEK-293) and human kidney adenocarcinoma cells (ACHN). Cells were exposed to different concentrations of (1.0–200 μM) cyanotoxin variants for 24 h and the cytotoxic effects were evaluated by Sulphorhodamine B (SRB) assay. Overall findings of the study demonstrate that cyanotoxins could cause cytotoxic effects on kidney cells. MC-LR was the most toxic while MC-LW was least toxic cyanotoxin on both cell types tested. MC-RR, MC-LF and Nodularin had moderate cytotoxicity on human renal cells. |
en_US |
dc.language.iso |
en |
en_US |
dc.subject |
Cytotoxicity |
en_US |
dc.subject |
ACHN cells |
en_US |
dc.subject |
HEK-293 cells |
en_US |
dc.subject |
SRB |
en_US |
dc.subject |
Cyanotoxins. |
en_US |
dc.title |
Comparative Cytotoxicity of Selected Cyanotoxins on Human Embryonic Kidney (HEK-293) and Human Kidney Adenocarcinoma (ACHN) Cells |
en_US |
dc.type |
Article |
en_US |
dc.date.published |
2016 |
|