Evaluation of Aqueous Leaf Extract of Cardiospermum halicacabum (L.) on Fertility of Male Rats

dc.contributor.author	Peiris, L.D.C.
dc.contributor.author	Dhaniishka, M.A.T.
dc.contributor.author	Jayathilake, T.A.H.D.G.
dc.date.accessioned	2017-10-23T04:23:17Z
dc.date.available	2017-10-23T04:23:17Z
dc.date.issued	2015
dc.identifier.citation	Peiris, L.D.C., Dhaniishka, M.A.T., Jayathilake, T.A.H.D.G. (2015). "Evaluation of Aqueous Leaf Extract of Cardiospermum halicacabum (L.) on Fertility of Male Rats", BioMed Research International, PP. 01-06	en_US, si_LK
dc.identifier.uri	http://dr.lib.sjp.ac.lk/handle/123456789/6008
dc.description.abstract	Attached	en_US, si_LK
dc.description.abstract	Treatment with 100 mg/kg and 200 mg/kg body weight of aqueous leaf extract (ALE) of Cardiospermum halicacabum for 30 days produced a significant dose dependent increase in the sperm counts and sperm motility in both caput and cauda regions. Further, significant increase in serum testosterone level was evident at all applied doses. However, no significant changes in the weight of sex organs were observed. Aqueous leaf extract also increased the number of females impregnated, number of implantations, and number of viable fetuses while decreasing the total number of resorption sites in the pregnant females. However, the total cholesterol level in the serum remained unchanged and there were no records on renotoxicity; nevertheless ALE exhibited a hepatoprotective effect. It was concluded that aqueous leaf extract of Cardiospermum halicacabum enhanced sperm concentration, motility, and testosterone, leading to positive results in fertility
dc.language.iso	en_US	en_US, si_LK
dc.publisher	BioMed Research International	en_US, si_LK
dc.title	Evaluation of Aqueous Leaf Extract of Cardiospermum halicacabum (L.) on Fertility of Male Rats	en_US, si_LK
dc.type	Article	en_US, si_LK